Correction: CYP2C9 Genotype vs. Metabolic Phenotype for Individual Drug Dosing—A Correlation Analysis Using Flurbiprofen as Probe Drug
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چکیده
There is an error in the third sentence of the second paragraph of the " Subjects and treatment " subsection of the Methods. The correct sentence is: According to the study design, which also designated phenotyping for CYP2D6, 10 mg dextromethorphan in water (DEX, as dextrome-thorphan hydrobromide monohydrate, Fagron, Barsbüttel, Germany) had been administered simultaneously. article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
CYP2C9 Genotype vs. Metabolic Phenotype for Individual Drug Dosing—A Correlation Analysis Using Flurbiprofen as Probe Drug
Currently, genotyping of patients for polymorphic enzymes responsible for metabolic elimination is considered a possibility to adjust drug dose levels. For a patient to profit from this procedure, the interindividual differences in drug metabolism within one genotype should be smaller than those between different genotypes. We studied a large cohort of healthy young adults (283 subjects), corre...
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